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[tutorial] NGS数据比对工具持续收集

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发表于 2016-9-1 10:38:52 | 显示全部楼层 |阅读模式
转载自生信菜鸟团:http://www.bio-info-trainee.com/1051.html
无意中看到了这个网站,比wiki的还有全面和专业。搜集了现有还算比较出名的比对软件,并且列出来了,还做了简单评价,里面对比对工具的收集,主要是基于2012年的一个综述《Tools for mapping high-throughput sequencing data》,相信应该是有不少人都看过这篇综述的,其实生物信息初学者应该自己去文献数据库找点感兴趣的关键词的综述多看看,广泛涉猎总没有坏处的。

文献链接:http://www.ncbi.nlm.nih.gov/pubmed/23060614
AbstractMOTIVATION: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task, numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial.
RESULTS: This survey focuses on classifying mappers through a wide number of characteristics. The goal is to allow practitioners to compare the mappers more easily and find those that are most suitable for their specific problem.
图中我比较熟悉的比对工具有 blast/bwa/bowtie/soap/gsnap/tophat/hisat/star

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